Publications

For a complete list, please visit PubMed.

Mesenchymal stromal cells donate mitochondria to articular chondrocytes exposed to mitochondrial, environmental, and mechanical stress. Fahey M, Bennett M, Thomas M, Montney K, Vivancos-Koopman I, Pugliese B, Browning L, Bonassar LJ, Delco M. Sci Rep. 2022 Dec 13;12(1):21525. doi: 10.1038/s41598-022-25844-5. PMID: 36513773; PMCID: PMC9747781.

STRAINS: A big data method for classifying cellular response to stimuli at the tissue scale. Zheng J, Wyse Jackson T, Fortier LA, Bonassar LJ, Delco ML, Cohen I. PLoS One. 2022 Dec 8;17(12):e0278626. doi: 10.1371/journal.pone.0278626. PMID: 36480531; PMCID: PMC9731430.

Controlling collagen gelation pH to enhance biochemical, structural, and biomechanical properties of tissue-engineered menisci. Kim J, Bonassar LJ. J Biomed Mater Res A. 2022 Oct 27. doi: 10.1002/jbm.a.37464. Epub ahead of print. PMID: 36300869.

Pre-glycation impairs gelation of high concentration collagen solutions. Diamantides N, Slyker L, Martin S, Rodriguez MR, Bonassar LJ. J Biomed Mater Res A. 2022 Dec;110(12):1953-1963. doi: 10.1002/jbm.a.37431. Epub 2022 Aug 11. PMID: 36183358; PMCID: PMC9648490.

Simple synthesis of soft, tough, and cytocompatible biohybrid composites. Darkes-Burkey C, Liu X, Slyker L, Mulderrig J, Pan W, Giannelis EP, Shepherd RF, Bonassar LJ, Bouklas N. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2116675119. doi: 10.1073/pnas.2116675119. Epub 2022 Jul 8. PMID: 35867753; PMCID: PMC9282227.

Efficient engineering of human auricular cartilage through mesenchymal stem cell chaperoning. Dong X, Askinas C, Kim J, Sherman JE, Bonassar LJ, Spector JA. J Tissue Eng Regen Med. 2022 Sep;16(9):825-835. doi: 10.1002/term.3332. Epub 2022 Jun 11. PMID: 35689509.

Off-the-Shelf Nipple Engineering: Neonipple Formation via Implantation of Scaffolded Decellularized Ovine Xenograft. Vernice NA, Caughey S, Berri N, Harris J, Matavosian A, Dong X, Bender RJ, Bonassar LJ, Spector JA. Ann Plast Surg. 2022 May 1;88(3 Suppl 3):S302-S308. doi: 10.1097/SAP.0000000000003184. PMID: 35513336; PMCID: PMC9097005.

The degenerative impact of hyperglycemia on the structure and mechanics of developing murine intervertebral discs. Lintz M, Walk RE, Tang SY, Bonassar LJ. JOR Spine. 2022 Feb 23;5(1):e1191. doi: 10.1002/jsp2.1191. PMID: 35386755; PMCID: PMC8966876.

Polyacrylamide hydrogel lubricates cartilage after biochemical degradation and mechanical injury. Vishwanath K, McClure SR, Bonassar LJ. J Orthop Res. 2023 Jan;41(1):63-71. doi: 10.1002/jor.25340. Epub 2022 Apr 20. PMID: 35384042.

Structural origins of cartilage shear mechanics. Wyse Jackson T, Michel J, Lwin P, Fortier LA, Das M, Bonassar LJ, Cohen I. Sci Adv. 2022 Feb 11;8(6):eabk2805. doi: 10.1126/sciadv.abk2805. Epub 2022 Feb 11. PMID: 35148179; PMCID: PMC8836800.
Innovative Biological Treatment Methods for Degenerative Disc Disease. Kirnaz S, Singh S, Capadona C, Lintz M, Goldberg JL, McGrath LB Jr, Medary B, Sommer F, Bonassar LJ, Härtl R. World Neurosurg. 2022 Jan;157:282-299. doi: 10.1016/j.wneu.2021.09.068. PMID: 34929786.
Rigidity and fracture of biopolymer double networks. Lwin P, Sindermann A, Sutter L, Wyse Jackson T, Bonassar LJ, Cohen I, Das M. Soft Matter. 2022 Jan 5;18(2):322-327. doi: 10.1039/d1sm00802a. PMID: 34881769.
Non-Destructive Spatial Mapping of Glycosaminoglycan Loss in Native and Degraded Articular Cartilage Using Confocal Raman Microspectroscopy. Gao T, Boys AJ, Zhao C, Chan K, Estroff LA, Bonassar LJ. Front Bioeng Biotechnol. 2021 Oct 28;9:744197. doi: 10.3389/fbioe.2021.744197. PMID: 34778225; PMCID: PMC8581176.
Depth-dependent patterns in shear modulus of temporomandibular joint cartilage correspond to tissue structure and anatomic location. Gologorsky CJ, Middendorf JM, Cohen I, Bonassar LJ. J Biomech. 2021 Dec 2;129:110815. doi: 10.1016/j.jbiomech.2021.110815. Epub 2021 Oct 15. PMID: 34706301.

Three-Dimensional-Printed External Scaffolds Mitigate Loss of Volume and Topography in Engineered Elastic Cartilage Constructs. Dong X, Premaratne ID, Bernstein JL, Samadi A, Lin AJ, Toyoda Y, Kim J, Bonassar LJ, Spector JA. Cartilage. 2021 Dec;13(2_suppl):1780S-1789S. doi: 10.1177/19476035211049556. Epub 2021 Oct 12. PMID: 34636646; PMCID: PMC8804786.

Pathomechanism and Biomechanics of Degenerative Disc Disease: Features of Healthy and Degenerated Discs. Kirnaz S, Capadona C, Lintz M, Kim B, Yerden R, Goldberg JL, Medary B, Sommer F, McGrath LB Jr, Bonassar LJ, Härtl R. Int J Spine Surg. 2021 Apr;15(s1):10-25. doi: 10.14444/8052. Epub 2021 Apr 21. PMID: 34376493; PMCID: PMC8092938.
The influence of chondrocyte source on the manufacturing reproducibility of human tissue engineered cartilage. Middendorf JM, Diamantides N, Kim B, Dugopolski C, Kennedy S, Blahut E, Cohen I, Bonassar LJ. Acta Biomater. 2021 Sep 1;131:276-285. doi: 10.1016/j.actbio.2021.07.003. Epub 2021 Jul 8. PMID: 34245892.

Mechanical performance of collagen gels is dependent on purity, α1/α2 ratio, and telopeptides. Slyker L, Diamantides N, Kim J, Bonassar LJ. J Biomed Mater Res A. 2022 Jan;110(1):11-20. doi: 10.1002/jbm.a.37261. Epub 2021 Jul 8. PMID: 34236763.

Targeting calcium-related mechanotransduction in early OA. Delco ML, Bonassar LJ. Nat Rev Rheumatol. 2021 Aug;17(8):445-446. doi: 10.1038/s41584-021-00649-4. PMID: 34163062.
Nipple Engineering: Maintaining Nipple Geometry with Externally Scaffolded Processed Autologous Costal Cartilage. Samadi A, Premaratne ID, Wright MA, Bernstein JL, Lara DO, Kim J, Zhao R, Bonassar LJ, Spector JA. J Plast Reconstr Aesthet Surg. 2021 Oct;74(10):2596-2603. doi: 10.1016/j.bjps.2021.03.010. Epub 2021 Mar 24. PMID: 33863678.

The role of SLRPs and large aggregating proteoglycans in collagen fibrillogenesis, extracellular matrix assembly, and mechanical function of fibrocartilage. Lopez SG, Bonassar LJ. Connect Tissue Res. 2022 May;63(3):269-286. doi: 10.1080/03008207.2021.1903887. Epub 2021 Apr 26. PMID: 33726572.

Combining TGF-β1 and Mechanical Anchoring to Enhance Collagen Fiber Formation and Alignment in Tissue-Engineered Menisci. Kim J, Boys AJ, Estroff LA, Bonassar LJ. ACS Biomater Sci Eng. 2021 Feb 19. doi: 10.1021/acsbiomaterials.0c01791. Epub ahead of print. PMID: 33606521.

Interaction with Cartilage Increases the Viscosity of Hyaluronic Acid Solutions. Cook SG, Bonassar LJ. ACS Biomater Sci Eng. 2020 May 11. 6(5):2787-2795. doi: 10.1021/acsbiomaterials.0c00100. Epub 2020 Apr 23. PMID: 33463274.

Imaging the local biochemical content of native and injured intervertebral disc using Fourier transform infrared microscopy. Sloan SR Jr, Wipplinger C, Kirnaz S, Delgado R, Huang S, Shvets G, Härtl R, Bonassar LJ. JOR Spine. 2020 Sep 14;3(4):e1121. doi: 10.1002/jsp2.1121. PMID: 33392456

Microscale strain mapping demonstrates the importance of interface slope in the mechanics of cartilage repair. Irwin RM, Gao T, Boys AJ, Ortved K, Cohen I, Bonassar LJ. J Biomech. 2021 Jan 4. 114:110159. doi: 10.1016/j.jbiomech.2020.110159. Epub 2020 Dec 3. PMID: 33310276

Cartilage articulation exacerbates chondrocyte damage and death after impact injury. Ayala S, Delco ML, Fortier LA, Cohen I, Bonassar LJ. J Orthop Res. 2020 Dec 4. doi: 10.1002/jor.24936. Epub ahead of print. PMID: 33274781.

Inflammatory and Non-Inflammatory Synovial Fluids Exhibit New & Distinct Tribological Endotypes. Feeney E, Galesso D, Secchieri C, Oliviero F, Ramonda R, Bonassar LJ. J Biomech Eng. 2020 Jun 25. doi: 10.1115/1.4047628. PMID: 32577715.

Mineral Distribution Spatially Patterns Bone Marrow Stromal Cell Behavior on Monolithic Bone Scaffolds. Zhou H, Boys AJ, Harrod JB, Bonassar LJ, Estroff LA. Acta Biomater. 2020 Aug. 112:274-285. doi: 10.1016/j.actbio.2020.05.032. PMID: 32479819

Heterogeneous matrix deposition in human tissue engineered cartilage changes the local shear modulus and resistance to local construct buckling. Middendorf JM, Dugopolski C, Kennedy S, Blahut E, Cohen I, Bonassar LJ. J Biomech. 2020 May 22. 105:109760. doi: 10.1016/j.jbiomech.2020.109760. Epub 2020 Mar 24. PMID: 32276782.

Combined nucleus pulposus augmentation and annulus fibrosus repair prevents acute intervertebral disc degeneration after discectomy. Sloan SR Jr, Wipplinger C, Kirnaz S, Navarro-Ramirez R, Schmidt F, McCloskey D, Pannellini T, Schiavinato A, Härtl R, Bonassar LJ. Sci Transl Med. 2020 Mar 11;12(534). pii: eaay2380. doi: 10.1126/scitranslmed.aay2380. PMID: 32161108

Multiscale mechanics of tissue-engineered cartilage grown from human chondrocytes and human-induced pluripotent stem cells. Middendorf JM, Diamantides N, Shortkroff S, Dugopolski C, Kennedy S, Cohen I, Bonassar LJ. J Orthop Res. 2020 Mar 3. doi: 10.1002/jor.24643. [Epub ahead of print] PMID: 32125023

Distinct tribological endotypes of pathological human synovial fluid reveal characteristic biomarkers and variation in efficacy of viscosupplementation at reducing local strains in articular cartilage. Irwin RM, Feeney E, Secchieri C, Galesso D, Cohen I, Oliviero F, Ramonda R, Bonassar LJ. Osteoarthritis Cartilage. 2020 Feb 24. pii: S1063-4584(20)30096-0. doi: 10.1016/j.joca.2020.02.029. [Epub ahead of print] PMID: 32105835

Effect of Lubricin Mimetics on the Inhibition of Osteoarthritis in a Rat Anterior Cruciate Ligament Transection Model. Nemirov D, Nakagawa Y, Sun Z, Lebaschi A, Wada S, Carballo C, Deng XH, Putnam D, Bonassar LJ, Rodeo SA. Am J Sports Med. 2020 Mar;48(3):624-634. doi: 10.1177/0363546519898691. Epub 2020 Jan 31. PMID: 32004084

Integrin α10β1-Selected Mesenchymal Stem Cells Mitigate the Progression of Osteoarthritis in an Equine Talar Impact Model. Delco ML, Goodale M, Talts JF, Pownder SL, Koff MF, Miller AD, Nixon B, Bonassar LJ, Lundgren-Åkerlund E, Fortier LA. Am J Sports Med. 2020 Mar;48(3):612-623. doi: 10.1177/0363546519899087. Epub 2020 Jan 31. PMID: 32004077

A Century of Cartilage Tribology Research is Informing Lubrication Therapies. Bonnevie E, Bonassar LJ. J Biomech Eng. 2020 Jan 1. doi: 10.1115/1.4046045. [Epub ahead of print] PMID: 31956901

Influence of Block Length on Articular Cartilage Lubrication with a Diblock Bottle-Brush Copolymer. Sun Z, Bonassar LJ, Putnam D. ACS Appl Mater Interfaces. 2020 Jan 8;12(1):330-337. doi: 10.1021/acsami.9b18933. Epub 2019 Dec 19. PMID: 31855406

Mitoprotective therapy prevents rapid, strain-dependent mitochondrial dysfunction after articular cartilage injury. Bartell LR, Fortier LA, Bonassar LJ, Szeto HH, Cohen I, Delco ML. J Orthop Res. 2019 Dec 16. doi: 10.1002/jor.24567. [Epub ahead of print] PMID: 31840828

The clot thickens: Autologous and allogeneic fibrin sealants are mechanically equivalent in an ex vivo model of cartilage repair. Irwin RM, Bonassar LJ, Cohen I, Matuska AM, Commins J, Cole B, Fortier LA. PLoS One. 2019 Nov 8;14(11):e0224756. doi: 10.1371/journal.pone.0224756. eCollection 2019. PMID: 31703078

Stribeck Curve Analysis of Temporomandibular Joint Condylar Cartilage and Disc. Middendorf J, Albahrani S, Bonassar LJ. J Biomech Eng. 2019 Mar 1. doi: 10.1115/1.4045283. [Epub ahead of print] PMID: 31654071

Dynamics of Synovial Fluid Aggregation under Shear. Cook SG, Guan Y, Pacifici NJ, Brown CN, Czako E, Samak MS, Bonassar LJ, Gourdon D. Langmuir. 2019 Dec 3;35(48):15887-15896. doi: 10.1021/acs.langmuir.9b02028. Epub 2019 Oct 23. PMID: 31608639

Regulation of proteoglycan production by varying glucose concentrations controls fiber formation in tissue engineered menisci. McCorry MC, Kim J, Springer NL, Sandy J, Plaas A, Bonassar LJ. Acta Biomater. 2019 Dec;100:173-183. doi: 10.1016/j.actbio.2019.09.026. Epub 2019 Sep 20. PMID: 31546030

Resorbable plating system stabilizes tissue-engineered intervertebral discs implanted ex vivo in canine cervical spines. Mojica-Santiago JA, Lang GM, Navarro-Ramirez R, Hussain I, Hӓrtl R, Bonassar LJ. JOR Spine. 2018 Aug 30;1(3):e1031. doi: 10.1002/jsp2.1031. eCollection 2018 Sep. PMID: 31463449

Proteoglycan removal by chondroitinase ABC improves injectable collagen gel adhesion to annulus fibrosus. Jiang EY, Sloan SR Jr, Wipplinger C, Kirnaz S, Härtl R, Bonassar LJ. Acta Biomater. 2019 Oct 1;97:428-436. doi: 10.1016/j.actbio.2019.08.024. Epub 2019 Aug 16. PMID: 31425894

High density cell seeding affects the rheology and printability of collagen bioinks. Diamantides N, Dugopolski C, Blahut E, Kennedy S, Bonassar L. Biofabrication. 2019 Jul 25. doi: 10.1088/1758-5090/ab3524. [Epub ahead of print]

Understanding the Stiff-to-Compliant Transition of the Meniscal Attachments by Spatial Correlation of Composition, Structure, and Mechanics. Boys AJ, Kunitake JAMR, Henak CR, Cohen I, Estroff LA, Bonassar LJ. ACS Appl Mater Interfaces. 2019 Jul 18. doi: 10.1021/acsami.9b03595. [Epub ahead of print]

Top-down Fabrication of Spatially Controlled Mineral-Gradient Scaffolds for Interfacial Tissue Engineering. Boys AJ, Zhou H, Harrod JB, McCorry MC, Estroff LA, Bonassar LJ. ACS Biomater Sci Eng. 2019 Jun 10;5(6):2988-2997. doi: 10.1021/acsbiomaterials.9b00176. Epub 2019 May 7.

Boundary mode lubrication of articular cartilage with a biomimetic diblock copolymer. Sun Z, Feeney E, Guan Y, Cook SG, Gourdon D, Bonassar LJ, Putnam D. Proc Natl Acad Sci U S A. 2019 Jun 4. pii: 201900716. doi: 10.1073/pnas.1900716116. [Epub ahead of print]

Frictional characterization of injectable hyaluronic acids is more predictive of clinical outcomes than traditional rheological or viscoelastic characterization. Bonnevie ED, Galesso D, Secchieri C, Bonassar LJPLoS One. 2019 May 10;14(5):e0216702. doi: 10.1371/journal.pone.0216702. eCollection 2019.

Clinical doses of radiation reduce collagen matrix stiffness. Miller JP, Borde BH, Bordeleau F, Zanotelli MR, LaValley DJ, Parker DJ, Bonassar LJ, Pannullo SC, Reinhart-King CA. APL Bioeng. 2018 Apr 3;2(3):031901. doi: 10.1063/1.5018327. eCollection 2018 Sep.

Glycation of collagen matrices promotes breast tumor cell invasion. Suh YJ, Hall MS, Huang YL, Moon SY, Song W, Ma M, Bonassar LJ, Segall JE, Wu M. Integr Biol (Camb). 2019 May 1. pii: zyz011. doi: 10.1093/intbio/zyz011. [Epub ahead of print]

Temporal changes in synovial fluid composition and elastoviscous lubrication in the equine carpal fracture model. Feeney E, Peal BT, Inglis JE, Su J, Nixon AJ, Bonassar LJ, Reesink HL. J Orthop Res. 2019 May;37(5):1071-1079. doi: 10.1002/jor.24281. Epub 2019 Mar 28.

Stable recombinant production of codon-scrambled lubricin and mucin in human cells. Shurer CR, Wang Y, Feeney E, Head SE, Zhang VX, Su J, Cheng Z, Stark MA, Bonassar LJ, Reesink HL, Paszek MJ. Biotechnol Bioeng. 2019 Jun;116(6):1292-1303. doi: 10.1002/bit.26940. Epub 2019 Mar 8.

Cellular and Chemical Gradients to Engineer the Meniscus-to-Bone Insertion. Iannucci LE, Boys AJ, McCorry MC, Estroff LA, Bonassar LJAdv Healthc Mater. 2019 Apr;8(7):e1800806. doi: 10.1002/adhm.201800806. Epub 2018 Dec 10.

Mesenchymal Stem Cell-Seeded High-Density Collagen Gel for Annular Repair: 6-Week Results From In Vivo Sheep Models. Hussain I, Sloan SR Jr, Wipplinger C, Navarro-Ramirez R, Zubkov M, Kim E, Kirnaz S, Bonassar LJ, Härtl R. Neurosurgery. 2018 Nov 23. doi: 10.1093/neuros/nyy523. [Epub ahead of print]

Measurement of local diffusion and composition in degraded articular cartilage reveals the unique role of surface structure in controlling macromolecular transport. DiDomenico CD, Kaghazchi A, Bonassar LJJ Biomech. 2019 Jan 3;82:38-45. doi: 10.1016/j.jbiomech.2018.10.019. Epub 2018 Oct 25.

Tissue engineering the human auricle by auricular chondrocyte-mesenchymal stem cell co-implantation. Cohen BP, Bernstein JL, Morrison KA, Spector JA, Bonassar LJPLoS One. 2018 Oct 24;13(10):e0202356. doi: 10.1371/journal.pone.0202356. eCollection 2018.

The Effect of Charge and Mechanical Loading on Antibody Diffusion through the Articular Surface of Cartilage. DiDomenico C, Bonassar LJJ Biomech Eng. 2018 Oct 22. doi: 10.1115/1.4041768. [Epub ahead of print]

How can 50 years of solute transport data in articular cartilage inform the design of arthritis therapeutics? DiDomenico CD, Bonassar LJOsteoarthritis Cartilage. 2018 Jul 24. pii: S1063-4584(18)31378-5. doi: 10.1016/j.joca.2018.07.006. [Epub ahead of print] Review.

In vivo annular repair using high-density collagen gel seeded with annulus fibrosus cells. Moriguchi Y, Borde B, Berlin C, Wipplinger C, Sloan SR, Kirnaz S, Pennicooke B, Navarro-Ramirez R, Khair T, Grunert P, Kim E, Bonassar LJ, Härtl R. Acta Biomater. 2018 Jul 5. pii: S1742-7061(18)30402-1. doi: 10.1016/j.actbio.2018.07.008. [Epub ahead of print]

Molecular transport in articular cartilage – what have we learned from the past 50 years? DiDomenico CD, Lintz M, Bonassar LJNat Rev Rheumatol. 2018 Jul;14(7):393-403. doi: 10.1038/s41584-018-0033-5. Review.

Microscale frictional strains determine chondrocyte fate in loaded cartilage. Bonnevie ED, Delco ML, Bartell LR, Jasty N, Cohen I, Fortier LA, Bonassar LJJ Biomech. 2018 Jun 6;74:72-78. doi: 10.1016/j.jbiomech.2018.04.020. Epub 2018 Apr 25.

Tissue Engineering Auricular Cartilage Using Late Passage Human Auricular Chondrocytes. Bernstein JL, Cohen BP, Lin A, Harper A, Bonassar LJ, Spector JA. Ann Plast Surg. 2018 Apr;80(4 Suppl 4):S168-S173. doi: 10.1097/SAP.0000000000001400.

Local and global measurements show that damage initiation in articular cartilage is inhibited by the surface layer and has significant rate dependence. Bartell LR, Xu MC, Bonassar LJ, Cohen I. J Biomech. 2018 Apr 27;72:63-70. doi: 10.1016/j.jbiomech.2018.02.033. Epub 2018 Mar 2.

Mitoprotective therapy preserves chondrocyte viability and prevents cartilage degeneration in an ex vivo model of posttraumatic osteoarthritis. Delco ML, Bonnevie ED, Szeto HS, Bonassar LJ, Fortier LA. J Orthop Res. 2018 Feb 22. doi: 10.1002/jor.23882. [Epub ahead of print]

Next Generation Tissue Engineering of Orthopedic Soft Tissue-to-Bone Interfaces. Boys AJ, McCorry MC, Rodeo S, Bonassar LJ, Estroff LA. MRS Commun. 2017 Sep;7(3):289-308. doi: 10.1557/mrc.2017.91. Epub 2017 Oct 3.

Biologic Annulus Fibrosus Repair: A Review of Preclinical In Vivo Investigations. Sloan SR Jr, Lintz M, Hussain I, Härtl R, Bonassar LJTissue Eng Part B Rev. 2017 Nov 4. doi: 10.1089/ten.TEB.2017.0351. [Epub ahead of print]

Degradation Alters the Lubrication of Articular Cartilage by High Viscosity, Hyaluronic Acid-Based Lubricants. Bonnevie ED, Galesso D, Secchieri C, Bonassar LJJ Orthop Res. 2017 Oct 25. doi: 10.1002/jor.23782. [Epub ahead of print]

Total disc replacement using tissue-engineered intervertebral discs in the canine cervical spine. Moriguchi Y, Mojica-Santiago J, Grunert P, Pennicooke B, Berlin C, Khair T, Navarro-Ramirez R, Ricart Arbona RJ, Nguyen J, Härtl R, Bonassar LJPLoS One. 2017 Oct 20;12(10):e0185716. doi: 10.1371/journal.pone.0185716. eCollection 2017.

In vitro culture increases mechanical stability of human tissue engineered cartilage constructs by prevention of microscale scaffold buckling. Middendorf JM, Shortkroff S, Dugopolski C, Kennedy S, Siemiatkoski J, Bartell LR, Cohen I, Bonassar LJ. J Biomech. 2017 Sep 14. pii: S0021-9290(17)30463-3. doi: 10.1016/j.jbiomech.2017.09.007. [Epub ahead of print]

Three-Dimensional Bioprinting and Its Potential in the Field of Articular Cartilage Regeneration. Mouser VHM, Levato R, Bonassar LJ, D’Lima DD, Grande DA, Klein TJ, Saris DBF, Zenobi-Wong M, Gawlitta D, Malda J. Cartilage. 2017 Oct;8(4):327-340. doi: 10.1177/1947603516665445. Epub 2016 Sep 1.

Annulus Fibrosus Repair Using High-Density Collagen Gel: An In vivo Ovine Model. Pennicooke B, Hussain I, Berlin C, Sloan SR, Borde B, Moriguchi Y, Lang G, Navarro-Ramirez R, Cheetham J, Bonassar LJ, Härtl R. Spine (Phila Pa 1976). 2017 Jul 17. doi: 10.1097/BRS.0000000000002334. [Epub ahead of print]

Synergistic Interactions of a Synthetic Lubricin-Mimetic with Fibronectin for Enhanced Wear Protection. Andresen Eguiluz RC, Cook SG, Tan M, Brown CN, Pacifici NJ, Samak MS, Bonassar LJ, Putnam D, Gourdon D. Front Bioeng Biotechnol. 2017 Jun 28;5:36. doi: 10.3389/fbioe.2017.00036. eCollection 2017.

Mitochondrial dysfunction is an acute response of articular chondrocytes to mechanical injury. Delco ML, Bonnevie ED, Bonassar LJ, Fortier LA. J Orthop Res. 2017 Jul 11. doi: 10.1002/jor.23651. [Epub ahead of print]

Correlating rheological properties and printability of collagen bioinks: the effects of riboflavin photocrosslinking and pH. Diamantides N, Wang L, Pruiksma T, Siemiatkoski J, Dugopolski C, Shortkroff S, Kennedy S, Bonassar LJBiofabrication. 2017 Jul 5;9(3):034102. doi: 10.1088/1758-5090/aa780f.

The Effect of Antibody Size and Mechanical Loading on Solute Diffusion Through the Articular Surface of Cartilage. DiDomenico CD, Goodearl A, Yarilina A, Sun V, Mitra S, Sterman AS, Bonassar LJJ Biomech Eng. 2017 Sep 1;139(9). doi: 10.1115/1.4037202.

Initial investigation of individual and combined annulus fibrosus and nucleus pulposus repair ex vivo. Sloan SR Jr, Galesso D, Secchieri C, Berlin C, Hartl R, Bonassar LJActa Biomater. 2017 Sep 1;59:192-199. doi: 10.1016/j.actbio.2017.06.045. Epub 2017 Jun 29.

Degenerative changes of the canine cervical spine after discectomy procedures, an in vivo study. Grunert P, Moriguchi Y, Grossbard BP, Ricart Arbona RJ, Bonassar LJ, Härtl R. BMC Vet Res. 2017 Jun 23;13(1):193. doi: 10.1186/s12917-017-1105-5.

Customized biomaterials to augment chondrocyte gene therapy. Aguilar IN, Trippel S, Shi S, Bonassar LJActa Biomater. 2017 Apr 15;53:260-267. doi: 10.1016/j.actbio.2017.02.008. Epub 2017 Feb 7.

Mechanical properties and structure-function relationships of human chondrocyte-seeded cartilage constructs after in vitro culture. Middendorf JM, Griffin DJ, Shortkroff S, Dugopolski C, Kennedy S, Siemiatkoski J, Cohen I, Bonassar LJ. J Orthop Res. 2017 Feb 7. doi: 10.1002/jor.23535. [Epub ahead of print]

Sub-critical impact inhibits the lubricating mechanisms of articular cartilage. Bonnevie ED, Delco ML, Galesso D, Secchieri C, Fortier LA, Bonassar LJJ Biomech. 2017 Feb 28;53:64-70. doi: 10.1016/j.jbiomech.2016.12.034. Epub 2016 Dec 29.

Matrix stiffening promotes a tumor vasculature phenotype. Bordeleau F, Mason BN, Lollis EM, Mazzola M, Zanotelli MR, Somasegar S, Califano JP, Montague C, LaValley DJ, Huynh J, Mencia-Trinchant N, Negrón Abril YL, Hassane DC, Bonassar LJ, Butcher JT, Weiss RS, Reinhart-King CA. Proc Natl Acad Sci U S A. 2016 Dec 29. pii: 201613855. doi: 10.1073/pnas.1613855114. [Epub ahead of print]

A Model System for Developing a Tissue Engineered Meniscal Enthesis. McCorry MC, Mansfield MM, Sha X, Coppola DJ, Lee JW, Bonassar LJ. Acta Biomater. 2016 Oct 28. pii: S1742-7061(16)30582-7. doi: 10.1016/j.actbio.2016.10.040. [Epub ahead of print]

Fiber Development and Matrix Production in Tissue Engineered Menisci using Bovine Mesenchymal Stem Cells and Fibrochondrocytes. McCorry MC, Bonassar LJ. Connect Tissue Res. 2016 Dec 7. [Epub ahead of print]

Optimizing cell sourcing for clinical translation of tissue engineered ears. Morrison KA, Cohen BP, Asanbe O, Dong X, Harper A, Bonassar LJ, Spector JA. Biofabrication. 2016 Dec 5;9(1):015004.

Hypoxic Expansion of Human Mesenchymal Stem Cells Enhances 3D Maturation of Tissue Engineered Intervertebral Discs. Hudson KD, Bonassar LJ. Tissue Eng Part A. 2016 Nov 30. [Epub ahead of print]

Cyclic Mechanical Loading Enhances Transport of Antibodies Into Articular Cartilage. DiDomenico CD, Xiang Wang Z, Bonassar LJ. J Biomech Eng. 2017 Jan 1;139(1). doi: 10.1115/1.4035265.

Human talar and femoral cartilage have distinct mechanical properties near the articular surface. Henak CR, Ross KA, Bonnevie ED, Fortier LA, Cohen I, Kennedy JG, Bonassar LJ. J Biomech. 2016 Oct 3;49(14):3320-3327. doi: 10.1016/j.jbiomech.2016.08.016.

Post-traumatic osteoarthritis of the ankle: A distinct clinical entity requiring new research approaches. Delco ML, Kennedy JG, Bonassar LJ, Fortier LA. J Orthop Res. 2016 Oct 20. doi: 10.1002/jor.23462. [Epub ahead of print] Review.

Human talar and femoral cartilage have distinct mechanical properties near the articular surface. Henak CR, Ross KA, Bonnevie ED, Fortier LA, Cohen I, Kennedy JG, Bonassar LJ. J Biomech. 2016 Aug 24. pii: S0021-9290(16)30901-0. doi: 10.1016/j.jbiomech.2016.08.016.

Biological Treatment Approaches for Degenerative Disk Disease: A Literature Review of In Vivo Animal and Clinical Data. Moriguchi Y, Alimi M, Khair T, Manolarakis G, Berlin C, Bonassar LJ, Härtl R. Global Spine J. 2016 Aug;6(5):497-518. doi: 10.1055/s-0036-1571955. Epub 2016 Jan 27. Review.

Binding and lubrication of biomimetic boundary lubricants on articular cartilage. Samaroo KJ, Tan M, Putnam D, Bonassar LJ. J Orthop Res. 2016 Jul 15. doi: 10.1002/jor.23370. [Epub ahead of print]

Hyaline Articular Matrix Formed by Dynamic Self-Regenerating Cartilage and Hydrogels. Meppelink AM, Zhao X, Griffin DJ, Erali R, Gill TJ, Bonassar LJ, Redmond RW, Randolph MA. Tissue Eng Part A. 2016 Jul;22(13-14):962-70. doi: 10.1089/ten.TEA.2015.0577. Epub 2016 Jul 7.

Physiologically Distributed Loading Patterns Drive the Formation of Zonally Organized Collagen Structures in Tissue-Engineered Meniscus. Puetzer JL, Bonassar LJ. Tissue Eng Part A2016 Jul;22(13-14):907-16. doi: 10.1089/ten.TEA.2015.0519. Epub 2016 Jun 27.

The effect of hypoxia on thermosensitive poly(N-vinylcaprolactam) hydrogels with tunable mechanical integrity for cartilage tissue engineering. Lynch B, Crawford K, Baruti O, Abdulahad A, Webster M, Puetzer J, Ryu C, Bonassar LJ, Mendenhall J. J Biomed Mater Res B Appl Biomater. 2016 May 30. doi: 10.1002/jbm.b.33705.

Galectin-3 Binds to Lubricin and Reinforces the Lubricating Boundary Layer of Articular Cartilage. Reesink HL, Bonnevie ED, Liu S, Shurer CR, Hollander MJ, Bonassar LJ, Nixon AJ. Sci Rep. 2016 May 9;6:25463. doi: 10.1038/srep25463.

Characterization of mesenchymal stem cells and fibrochondrocytes in three-dimensional co-culture: analysis of cell shape, matrix production, and mechanical performance. McCorry MC, Puetzer JL, Bonassar LJ. Stem Cell Res Ther. 2016 Mar 12;7(1):39. doi: 10.1186/s13287-016-0301-8.

Long-Term Morphological and Microarchitectural Stability of Tissue-Engineered, Patient-Specific Auricles In Vivo. Cohen BP, Hooper RC, Puetzer JL, Nordberg R, Asanbe O, Hernandez KA, Spector JA, Bonassar LJ. Tissue Eng Part A. 2016 Mar 14. [Epub ahead of print]

Biomechanical and biochemical characterization of porcine tracheal cartilage. Hoffman B, Martin M, Brown BN, Bonassar LJ, Cheetham J. Laryngoscope. 2016 Jan 30. doi: 10.1002/lary.25861. [Epub ahead of print]

Elastoviscous Transitions of Articular Cartilage Reveal a Mechanism of Synergy between Lubricin and Hyaluronic Acid. Bonnevie ED, Galesso D, Secchieri C, Cohen I, Bonassar LJ. PLoS One. 2015 Nov 24;10(11):e0143415. doi: 10.1371/journal.pone.0143415. eCollection 2015.

Comparison of Efficacy of Endogenous and Exogenous IGF-I in Stimulating Matrix Production in Neonatal and Mature Chondrocytes. Aguilar IN, Trippel SB, Shi S, Bonassar LJ. Cartilage. 2015 Jun 11. doi: 10.1177/1947603515578691.

Mechanical properties and structure-function relationships in articular cartilage repaired using IGF-I gene-enhanced chondrocytes. Griffin DJ, Ortved KF, Nixon AJ, Bonassar LJ. J Orthop Res. 2015 Aug 26. doi: 10.1002/jor.23038. [Epub ahead of print]

Fibronectin mediates enhanced wear protection of lubricin during shear. Andresen Eguiluz RC, Cook SG, Brown CN, Wu F, Pacifici NJ, Bonassar LJ, Gourdon D. Biomacromolecules. 2015 Aug 6. [Epub ahead of print]

Measuring microscale strain fields in articular cartilage during rapid impact reveals thresholds for chondrocyte death and a protective role for the superficial layer. Bartell LR, Fortier LA, Bonassar LJ, Cohen I. J Biomech. 2015 Jun 12. pii: S0021-9290(15)00325-5. doi: 10.1016/j.jbiomech.2015.05.035. [Epub ahead of print]

Cell and protein compatible 3D bioprinting of mechanically strong constructs for bone repair. Sawkins MJ, Mistry P, Brown BN, Shakesheff KM, Bonassar LJ, Yang J. Biofabrication. 2015 Jul 2;7(3):035004. doi: 10.1088/1758-5090/7/3/035004.

Riboflavin crosslinked high-density collagen gel for the repair of annular defects in intervertebral discs: An in vivo study. Grunert P, Borde BH, Towne SB, Moriguchi Y, Hudson KD, Bonassar LJ, Härtl R. Acta Biomater. 2015 Jun 23. pii: S1742-7061(15)00271-8. doi: 10.1016/j.actbio.2015.06.006. [Epub ahead of print]

Mechanical Characterization of Matrix-Induced Autologous Chondrocyte Implantation (MACI®) Grafts in an Equine Model at 53 weeks. Griffin D, Bonnevie E, Lachowsky D, Hart J, Sparks H, Moran N, Matthews G, Nixon A, Cohen I, and Bonassar LJ,  J. Biomech., 2015 Apr 15. [Accepted Manuscript]

Induction of fiber alignment and mechanical anisotropy in tissue engineered menisci with mechanical anchoring. Puetzer JL, Koo E, Bonassar LJ. J Biomech. 2015 Feb 26. pii: S0021-9290(15)00123-2. doi: 10.1016/j.jbiomech.2015.02.033. [Epub ahead of print]

Joint-dependent response to impact and implications for post-traumatic osteoarthritis. Novakofski KD, Berg LC, Bronzini I, Bonnevie ED, Poland SG, Bonassar LJ, Fortier LA. Osteoarthritis Cartilage. 2015 Feb 26. pii: S1063-4584(15)00067-9. doi: 10.1016/j.joca.2015.02.023. [Epub ahead of print]

Dose-dependent response of tissue-engineered intervertebral discs to dynamic unconfined compressive loading. Hudson KD, Mozia RI, Bonassar LJ. Tissue Eng Part A. 2015 Feb;21(3-4):564-72. doi: 10.1089/ten.TEA.2014.0174. Epub 2015 Jan 19.

Injectable, high-density collagen gels for annulus fibrosus repair: An in vitro rat tail model. Borde B, Grunert P, Härtl R, Bonassar LJ. J Biomed Mater Res A. 2014 Dec 11. doi: 10.1002/jbm.a.35388. [Epub ahead of print]

Effects of enzymatic treatments on the depth-dependent viscoelastic shear properties of articular cartilage. Griffin DJ, Vicari J, Buckley MR, Silverberg JL, Cohen I, Bonassar LJ. J Orthop Res. 2014 Dec;32(12):1652-7. doi: 10.1002/jor.22713. Epub 2014 Sep 5.

Structure-function relations and rigidity percolation in the shear properties of articular cartilage. Silverberg JL, Barrett AR, Das M, Petersen PB, Bonassar LJ, Cohen I. Biophys J. 2014 Oct 7;107(7):1721-30. doi: 10.1016/j.bpj.2014.08.011.

Adhesion and integration of tissue engineered cartilage to porous polyethylene for composite ear reconstruction. O’Sullivan NA, Kobayashi S, Ranka MP, Zaleski KL, Yaremchuk MJ, Bonassar LJ, Randolph MA. J Biomed Mater Res B Appl Biomater. 2014 Sep 6. doi: 10.1002/jbm.b.33269. [Epub ahead of print]

Enhanced boundary lubrication properties of engineered menisci by lubricin localization with insulin-like growth factor I treatment. Bonnevie ED, Puetzer JL, Bonassar LJ. J Biomech. 2014 Jun 27;47(9):2183-8. doi: 10.1016/j.jbiomech.2013.10.028. Epub 2013 Oct 22.

Computed tomography-guided tissue engineering of upper airway cartilage. Brown BN, Siebenlist NJ, Cheetham J, Ducharme NG, Rawlinson JJ, Bonassar LJ. Tissue Eng Part C Methods. 2014 Jun;20(6):506-13. doi: 10.1089/ten.TEC.2013.0216. Epub 2013 Dec 11.

Tissue-engineered intervertebral discs: MRI results and histology in the rodent spine. Grunert P, Gebhard HH, Bowles RD, James AR, Potter HG, Macielak M, Hudson KD, Alimi M, Ballon DJ, Aronowitz E, Tsiouris AJ, Bonassar LJ, Härtl R. J Neurosurg Spine. 2014 Apr;20(4):443-51. doi: 10.3171/2013.12.SPINE13112. Epub 2014 Feb 14.

Assessment of intervertebral disc degeneration based on quantitative magnetic resonance imaging analysis: an in vivo study. Grunert P, Hudson KD, Macielak MR, Aronowitz E, Borde BH, Alimi M, Njoku I, Ballon D, Tsiouris AJ, Bonassar LJ, Härtl R. Spine (Phila Pa 1976). 2014 Mar 15;39(6):E369-78. doi: 10.1097/BRS.0000000000000194.

Identification of cartilage injury using quantitative multiphoton microscopy. Novakofski KD, Williams RM, Fortier LA, Mohammed HO, Zipfel WR, Bonassar LJ. Osteoarthritis Cartilage. 2014 Feb;22(2):355-62. doi: 10.1016/j.joca.2013.10.008. Epub 2013 Nov 1.

Annular repair using high-density collagen gel: a rat-tail in vivo model. Grunert P, Borde BH, Hudson KD, Macielak MR, Bonassar LJ, Härtl R. Spine (Phila Pa 1976). 2014 Feb 1;39(3):198-206. doi: 10.1097/BRS.0000000000000103.

Quantitative characterization of mesenchymal stem cell adhesion to the articular cartilage surface. Hung BP, Babalola OM, Bonassar LJ. J Biomed Mater Res A. 2013 Dec;101(12):3592-8. doi: 10.1002/jbm.a.34647. Epub 2013 Jun 7.

Spatial periodicity in growth plate shear mechanical properties is disrupted by vitamin D deficiency. Sevenler D, Buckley MR, Kim G, van der Meulen MC, Cohen I, Bonassar LJ. J Biomech. 2013 Jun 21;46(10):1597-603. doi: 10.1016/j.jbiomech.2013.04.023. Epub 2013 May 21.

High density type I collagen gels for tissue engineering of whole menisci. Puetzer JL, Bonassar LJ. Acta Biomater. 2013 May 10. doi:pii: S1742-7061(13)00234-1. 10.1016/j.actbio.2013.05.002. [Epub ahead of print] PMID: 23669622

High-fidelity tissue engineering of patient-specific auricles for reconstruction of pediatric microtia and other auricular deformities. Reiffel AJ, Kafka C, Hernandez KA, Popa S, Perez JL, Zhou S, Pramanik S, Brown BN, Ryu WS, Bonassar LJ, Spector JA. PLoS One. 2013;8(2):e56506. doi: 10.1371/journal.pone.0056506. Epub 2013 Feb 20

The Effect of IGF-I on Anatomically-shaped Tissue Engineered Menisci. Puetzer, JL, Brown, B, Ballyns, JJ, Bonassar, LJ. Tissue Eng Part A. 2013 [Epub ahead of print]

Anatomic variation of depth-dependent mechanical properties in neonatal bovine articular cartilage. Silverberg JL, Dillavou S, Bonassar LJ, Cohen I. J Orthop Res. 2012 Dec 31. doi: 10.1002/jor.22303. [Epub ahead of print]

Tissue-engineered total disc replacement: final outcomes of a murine caudal disc in vivo study. James AR, Bowles RD, Gebhard HH, Bonassar LJ, Härtl R. Evid Based Spine Care J. 2011 Nov;2(4):55-6. doi: 10.1055/s-0031-1274758.

Cell(MC3T3-E1)-printed poly(ϵ-caprolactone)/alginate hybrid scaffolds for tissue regeneration. Lee H, Ahn S, Bonassar LJ, Kim G. Macromol Rapid Commun. 2013 Jan 25;34(2):142-9. doi: 10.1002/marc.201200524. Epub 2012 Oct 12.

Rapid 3D printing of anatomically accurate and mechanically heterogeneous aortic valve hydrogel scaffolds. Hockaday LA, Kang KH, Colangelo NW, Cheung PY, Duan B, Malone E, Wu J, Girardi LN, Bonassar LJ, Lipson H, Chu CC, Butcher JT. Biofabrication. 2012 Sep;4(3):035005. doi: 10.1088/1758-5082/4/3/035005. Epub 2012 Aug 23.

Cells (MC3T3-E1)-laden alginate scaffolds fabricated by a modified solid-freeform fabrication process supplemented with an aerosol spraying.
Ahn S, Lee H, Bonassar LJ, Kim G. Biomacromolecules. 2012 Sep 10;13(9):2997-3003. doi: 10.1021/bm3011352. Epub 2012 Aug 30.

Tuning three-dimensional collagen matrix stiffness independently of collagen concentration modulates endothelial cell behavior.
Mason BN, Starchenko A, Williams RM, Bonassar LJ, Reinhart-King CA. Acta Biomater. 2013 Jan;9(1):4635-44. doi: 10.1016/j.actbio.2012.08.007. Epub 2012 Aug 16.

Properties of cartilage engineered from elderly human chondrocytes for articular surface repair.
Zhao X, Bichara DA, Ballyns FP, Yoo JJ, Ong W, Randolph MA, Bonassar LJ, Gill TJ. Tissue Eng Part A. 2012 Jul;18(13-14):1490-9. doi: 10.1089/ten.TEA.2011.0445. Epub 2012 Jun 5.

The effect of the duration of mechanical stimulation and post-stimulation culture on the structure and properties of dynamically compressed tissue-engineered menisci.
Puetzer JL, Ballyns JJ, Bonassar LJ. Tissue Eng Part A. 2012 Jul;18(13-14):1365-75. doi: 10.1089/ten.TEA.2011.0589. Epub 2012 Apr 26.

Mathematical modeling and frequency gradient analysis of cellular and vascular invasion into integra and strattice: toward optimal design of tissue regeneration scaffolds.
Reiffel AJ, Henderson PW, Krijgh DD, Belkin DA, Zheng Y, Bonassar LJ, Stroock AD, Spector JA. Plast Reconstr Surg. 2012 Jan;129(1):89-99.