Alexander Boys and Mary Clare McCorry published an article in MRS Communications.
Next generation tissue engineering of orthopedic soft tissue-to-bone interfacesÂ
This article reviews current strategies for tissue engineering soft tissue-to-bone interfaces, specifically the enthesis of tendons, ligaments, and the meniscus. The tissue engineering process is broken down into three sections: Materials processing methods, Cellular contributions, and Biochemical factors. These processes can be concurrently applied to produce a tissue engineered construct. Such a construct then undergoes maturation by stimulation through mechanical and chemical means before developing into an implantable construct. The review culminates in an outline of future challenges for the interfacial tissue engineering field.