A figure from an upcoming publication from the Bonassar lab is featured as the frontpiece ofAdvanced Healthcare Materials. The manuscript by Iannucci et al, is titled “Cellular and Chemical Gradients to Engineer the Meniscus-to-Bone Insertion” and is published in the July issue of Advanced Healthcare Materials, which focuses on biological interfaces. The paper describes the use of customized bioreactors and patterned deposition of mesenchymal stem cells and meniscal fibrochondrocytes to achieve more accurate and mechanically robust reconstruction of the meniscal enthesis, which anchors the meniscus to the tibia. The frontpiece image (see below and online at https://onlinelibrary.wiley.com/doi/10.1002/adhm.201970027) is a confocal reflectance micrograph showing fibrochondrocytes (green) and mesenchymal stem cells (red) interacting with a collagen matrix (yellow).
The first author, Leanne Iannucci, completed her BS and MEng degrees at Cornell University, working in the Bonassar lab to develop new methods to engineer hard-to-soft tissue interfaces. She is currently a PhD student in Biomedical Engineering at Washington University in St. Louis studying soft tissue biomechanics. Congratulations to Leanne and her co-authors!